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Path: ...!eternal-september.org!feeder3.eternal-september.org!nntp-feed.chiark.greenend.org.uk!ewrotcd!nntp.terraraq.uk!news1.firedrake.org!news.eyrie.org!beagle.ediacara.org!.POSTED.beagle.ediacara.org!not-for-mail From: Chris Thompson <the_thompsons@earthlink.net> Newsgroups: talk.origins Subject: Re: HHS cancels Moderna H5 influenza vaccine Date: Thu, 29 May 2025 22:30:53 -0400 Organization: A noiseless patient Spider Lines: 37 Sender: to%beagle.ediacara.org Approved: moderator@beagle.ediacara.org Message-ID: <101b591$9k14$1@dont-email.me> References: <101ar2n$409r$1@dont-email.me> MIME-Version: 1.0 Content-Type: text/plain; charset=UTF-8; format=flowed Content-Transfer-Encoding: 8bit Injection-Info: beagle.ediacara.org; posting-host="beagle.ediacara.org:3.132.105.89"; logging-data="7956"; mail-complaints-to="usenet@beagle.ediacara.org" User-Agent: Mozilla/5.0 (Windows NT 10.0; Win64; x64; rv:128.0) Gecko/20100101 Firefox/128.0 SeaMonkey/2.53.20 To: talk-origins@moderators.isc.org Cancel-Lock: sha1:uBj2v/2VNs+5oRBy8C1aFuINacI= Return-Path: <news@eternal-september.org> X-Original-To: talk-origins@ediacara.org Delivered-To: talk-origins@ediacara.org id 47E7922978C; Thu, 29 May 2025 22:31:06 -0400 (EDT) by beagle.ediacara.org (Postfix) with ESMTPS id D4A84229783 for <talk-origins@ediacara.org>; Thu, 29 May 2025 22:31:03 -0400 (EDT) by pi-dach.dorfdsl.de (8.18.1/8.18.1/Debian-6~bpo12+1) with ESMTPS id 54U2V1qD1118621 (version=TLSv1.3 cipher=TLS_AES_256_GCM_SHA384 bits=256 verify=NOT) for <talk-origins@moderators.isc.org>; Fri, 30 May 2025 04:31:01 +0200 (using TLSv1.3 with cipher TLS_AES_256_GCM_SHA384 (256/256 bits) key-exchange X25519 server-signature ECDSA (P-256) server-digest SHA256) (No client certificate requested) by smtp.eternal-september.org (Postfix) with ESMTPS id 4FF0D60A04 for <talk-origins@moderators.isc.org>; Fri, 30 May 2025 02:30:58 +0000 (UTC) Authentication-Results: name/4FF0D60A04; dmarc=fail (p=none dis=none) header.from=earthlink.net id E1FD4DC01CA; Fri, 30 May 2025 04:30:57 +0200 (CEST) X-Injection-Date: Fri, 30 May 2025 04:30:57 +0200 (CEST) X-Auth-Sender: U2FsdGVkX1/8+vktPBtfKaoWStTNgsxbDGIwhP6PdZvRXEnUcBS/ACYdxEZXL/px In-Reply-To: <101ar2n$409r$1@dont-email.me> HEADER_FROM_DIFFERENT_DOMAINS,NICE_REPLY_A,RCVD_IN_DNSWL_BLOCKED, RCVD_IN_ZEN_BLOCKED_OPENDNS,SPF_HELO_NONE,SPF_PASS,URIBL_BLOCKED, URIBL_DBL_BLOCKED_OPENDNS,URIBL_ZEN_BLOCKED_OPENDNS, USER_IN_WELCOMELIST,USER_IN_WHITELIST autolearn=ham autolearn_force=no version=3.4.6 smtp.eternal-september.org Bytes: 4580 RonO wrote: > https://www.cidrap.umn.edu/avian-influenza-bird-flu/hhs-cancels-funding-moderna-s-candidate-h5-avian-flu-and-pandemic-vaccines > > > This seems stupid since mRNA vaccines would be the fastest way to > respond to H5N1 if it ever does make the jump to human infection. They > would need an H5 vaccine that would produce antibodies that could > neutralize the virus. They already know that the virus has changed a > lot in the dairy herd, and they had to make a synthetic antigen with the > H5 genotype B3.13 sequence found in the Missouri patient in order to > look for neutralizing antibodies. They did initial testing on the Texas > B3.13 dairy virus and it was neutralized by antibodies produced by H5 > vaccine strains that the CDC had, but that obviously changed by the time > the Missouri patient was infected. In the case of the D1.1 genotype > that infected humans they didn't even try to test existing H5 vaccine > strains against it. The D1.1 H5 sequence is very different from the > B3.13 sequence. > > This just means that they need to make a vaccine to the virus that might > make the jump to humans. Apparently Moderna had a working vaccine, and > had gotten more funding to work it up, but that has been canceled. For > mRNA vaccines you can make the antigen any sequence that you want it to > be. It is the basis for making updated mRNA vaccines for Covid, and > would be expected to work for influenza. The H5 vaccine that the CDC > stockpiled is likely worthless against many of the variants currently > infecting cattle and dairy and poultry workers. > > Ron Okimoto > Worm-brain Kennedy Jr. is a known anti-vaxxer, and mRNA vaccines hold a special place in his list of things to eliminate from health care. He's criminally stupid and he's going to get lots of people killed. Chris They have Project 2025. We need Project 1792.