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From: John Larkin <jjSNIPlarkin@highNONOlandtechnology.com>
Newsgroups: sci.electronics.design
Subject: Re: OT: Dynamic DNA structures and the formation of memory
Date: Mon, 13 May 2024 09:31:31 -0700
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On Mon, 13 May 2024 17:01:27 +0200, Jeroen Belleman
<jeroen@nospam.please> wrote:

>On 5/13/24 16:10, John Larkin wrote:
>> On Mon, 13 May 2024 10:30:09 +0200, Jeroen Belleman
>> <jeroen@nospam.please> wrote:
>> 
>>> On 5/13/24 03:30, John Larkin wrote:
>>>> On Sun, 12 May 2024 21:21:56 -0400, "Tom Del Rosso"
>>>> <fizzbintuesday@that-google-mail-domain.com> wrote:
>>>>
>>>>> John Larkin wrote:
>>>>>> On Sun, 05 May 2024 05:36:06 GMT, Jan Panteltje
>>>>>> <pNaonStpealmtje@yahoo.com> wrote:
>>>>>>
>>>>>>> Dynamic DNA structures and the formation of memory
>>>>>>> https://www.sciencedaily.com/releases/2024/05/240501125755.htm
>>>>>>> Summary:
>>>>>>> An international collaborative research team has discovered that
>>>>>>> G-quadraplex DNA (G4-DNA) accumulates in neurons and dynamically
>>>>>>> controls the activation and repression of genes underlying long-term
>>>>>>> memory formation.
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>> I have always though that memory could be stored as DNA sequenxes...
>>>>>>
>>>>>> More likely RNA or some other protein.
>>>>>>
>>>>>> The oft-mocked Lamarckian concept, of genetic learning (not just
>>>>>> natural selection) is probably real, and some reverse transcription
>>>>>> does happen, namely that DNA is edited within the life of one
>>>>>> organism. But remembering where you left your glasses is probably
>>>>>> handled at a lower level than editing your chromosones.
>>>>>
>>>>> But how can it be passed down as Lamarck thought, if the eggs in the
>>>>> ovaries are formed early? If genetic memory could be passed down it
>>>>> would be only from the father because sperm are formed recently. But the
>>>>> sperm spawn from local cells. If DNA is edited to store memory then
>>>>> would these changes be duplicated in all cells in all tissues? How else
>>>>> would the changes get into sperm cells? How could they get into eggs?
>>>>>
>>>>
>>>> If it is advantageous for a woman's life experiences to be passed onto
>>>> her children, nature will find a way.
>>>>
>>>
>>> Yes, it's called 'education'. No need to invent improbable
>>> mechanisms without scientific basis.
>>>
>>> Jeroen Belleman
>> 
>> No sense in dismissing possibilities because you don't like them. That
>> applies to biology and electronics. Nature invents "improbable
>> mechanisms" which have a "scientific basis" when shown to exist.
>> 
>> The ideas of jumping genes, reverse transcription, and epignetic
>> switching were all mocked, known to be impossible, by the rigid
>> neo-Darwinists. I think there's all sorts of cool stuff waiting for
>> old farts to die so they can be considered and discovered.
>> Mitochondria are sadly neglected.
>> 
>> Evolution by random mutation and natural selection is for losers.
>> Losers are also known as lunch.
>> 
>
>You missed your vocation. You should have become a biologist.

My interest and talent is electronic design. Besides that, biology is
too slow. I can invent and simulate and test a new circuit in an
afternoon.


>
>
>> Most people, including most engineers, are instantly hostile to
>> unauthorized ideas. That's fine with me... it leaves me more stuff to
>> invent and sell.
>> 
>
>Most people judge the validity of new ideas in the context of their
>knowledge base. You have to have some way to quickly weed out
>the torrent of harebrained ideas, or you wouldn't get anything
>done at all. Yes, this can backfire.

Weeding out ideas, as a habit and a priority, is a good way to have no
ideas. Playing with ideas is better.

A human brain can play with multiple, literally millions, of ideas as
effortless parallel background process. In your sleep. If you let it.