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Subject: Anti-cancer furanocoumarines - kompendium wiedzy dla lekarzy i
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Date: Tue, 2 Jul 2024 21:54:58 +0000
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Open AccessArticle
Determining Antiradical Capacity of Medicinal Plant Extract Individual
Constituents Using Post-Column Reaction Method
by Jarosław L. Przybył, Jan Stefaniak, Anna Jaroszewicz, Amanda
Gawrońska, Marcin Łapiński, Katarzyna Barbara Bączek and Zenon Węglarz
Int. J. Mol. Sci. 2024, 25(10), 5461;
https://doi.org/10.3390/ijms25105461 - 17 May 2024
Viewed by 570
Abstract The post-column reaction method enables the evaluation of the
antiradical capacity of individual components in a mixture by separating
the components using HPLC and measuring stable free radical (e.g.,
DPPH●) scavenging that occurs after the chromatography column. The
equipment typically consists of two [...] Read more.
(This article belongs to the Special Issue Natural Products and
Synthetic Compounds for Drug Development)
► Show Figures
24 pages, 4748 KiB
Open AccessArticle
The Different Composition of Coumarins and Antibacterial Activity of
Phlojodicarpus sibiricus and Phlojodicarpus villosus Root Extracts
by Maria T. Khandy, Valeria P. Grigorchuk, Anastasia K. Sofronova and
Tatiana Y. Gorpenchenko
Plants 2024, 13(5), 601; https://doi.org/10.3390/plants13050601 - 22 Feb
2024
Viewed by 973
Abstract Phlojodicarpus sibiricus, a valuable endangered medicinal
plant, is a source of angular pyranocoumarins used in pharmacology. Due
to limited resource availability, other pyranocoumarin sources are
needed. In the present research, the chemical composition of a closely
related species, Phlojodicarpus villosus, was [...] Read more.
(This article belongs to the Special Issue Extraction Technologies,
Isolation, Separation, and Application of Phytochemicals Volume II)
► Show Figures
15 pages, 21439 KiB
Open AccessReview
Bergaptol, a Major Furocoumarin in Citrus: Pharmacological Properties
and Toxicity
by Pakkapong Phucharoenrak and Dunyaporn Trachootham
Molecules 2024, 29(3), 713; https://doi.org/10.3390/molecules29030713 -
4 Feb 2024
Cited by 1 | Viewed by 1288
Abstract Bergaptol (5-hydroxypsoralen or 5-hydroxyfuranocoumarin) is a
naturally occurring furanocoumarin widely found in citrus fruits, which
has multiple health benefits. Nonetheless, no specific review articles
on bergaptol have been published. Compiling updated information on
bergaptol is crucial in guiding future research direction and
application. [...] Read more.
(This article belongs to the Special Issue Biological Activity of
Phenolics and Polyphenols in Nature Products)
► Show Figures
28 pages, 2974 KiB
Open AccessReview
Methoxyfuranocoumarins of Natural Origin–Updating Biological Activity
Research and Searching for New Directions—A Review
by Magdalena Bartnik
Curr. Issues Mol. Biol. 2024, 46(1), 856-883;
https://doi.org/10.3390/cimb46010055 - 19 Jan 2024
Cited by 1 | Viewed by 1085
Abstract Plant secondary metabolites, including furanocoumarins, have
attracted attention for decades as active molecules with therapeutic
potential, especially those occurring in a limited number of species as
evolutionarily specific and chemotaxonomically important. The most
famous methoxyfuranocoumarins (MFCs), bergapten, xanthotoxin,
isopimpinellin, phellopterin, byakangelicol, byakangelicin,
isobergapten, [...] Read more.
(This article belongs to the Special Issue Molecular Research in
Bioactivity of Natural Products)
► Show Figures
17 pages, 3184 KiB
Open AccessArticle
Furanocoumarins as Enhancers of Antitumor Potential of Sorafenib and
LY294002 toward Human Glioma Cells In Vitro
by Joanna Sumorek-Wiadro, Adrian Zając, Krystyna Skalicka-Woźniak,
Wojciech Rzeski and Joanna Jakubowicz-Gil
Int. J. Mol. Sci. 2024, 25(2), 759; https://doi.org/10.3390/ijms25020759
- 7 Jan 2024
Viewed by 954
Abstract Furanocoumarins are naturally occurring compounds in the plant
world, characterized by low molecular weight, simple chemical structure,
and high solubility in most organic solvents. Additionally, they have a
broad spectrum of activity, and their properties depend on the location
and type of attached [...] Read more.
(This article belongs to the Special Issue The Occurrence, Evolution and
Treatment of Glioblastoma)
► Show Figures
25 pages, 7395 KiB
Open AccessReview
A Review on the Morphology, Cultivation, Identification, Phytochemistry,
and Pharmacology of Kitagawia praeruptora (Dunn) Pimenov
by Qi Wang, Lulu Ding, Ruihong Wang and Zongsuo Liang
Molecules 2023, 28(24), 8153; https://doi.org/10.3390/molecules28248153
- 18 Dec 2023
Viewed by 979
Abstract Kitagawia praeruptora (Dunn) Pimenov, commonly known as Qianhu
in China, is a widely used folk Chinese herbal medicine. This article
reviews its botanical traits, ethnopharmacology, cultivation techniques,
identification, phytochemical compositions, and pharmacological effects.
Over 70 coumarin compounds, including simple coumarins, pyranocoumarins,
and furanocoumarins, [...] Read more.
► Show Figures
15 pages, 3819 KiB
Open AccessArticle
Notopterol Suppresses IL-17-Induced Proliferation and Invasion of A549
Lung Adenocarcinoma Cells via Modulation of STAT3, NF-κB, and AP-1
Activation
by Sirinada Inthanon, Pornngarm Dejkriengkraikul and Supachai Yodkeeree
Int. J. Mol. Sci. 2023, 24(20), 15057;
https://doi.org/10.3390/ijms242015057 - 11 Oct 2023
Cited by 3 | Viewed by 1374
Abstract Interleukine-17 is a proinflammatory cytokine that promotes
lung cancer growth and progression though the activation of the STAT3,
NF-κB, and AP-1 signaling pathways. Therefore, blocking the
IL-17-induced oncogenic pathway is a new strategy for the treatment of
lung cancer. Notopterol, a furanocoumarin, has [...] Read more.
(This article belongs to the Special Issue Latest Research on
Anti-cancer, Anti-inflammatory, and Antioxidation Active Substances)
► Show Figures
14 pages, 739 KiB
Open AccessArticle
Cytotoxic, Anti-Hemolytic, and Antioxidant Activities of Ruta
chalepensis L. (Rutaceae) Extract, Fractions, and Isolated Compounds
by Joel H. Elizondo-Luévano, Nancy E. Rodríguez-Garza, Aldo F.
Bazaldúa-Rodríguez, César I. Romo-Sáenz, Patricia Tamez-Guerra, María J.
Verde-Star, Ricardo Gomez-Flores and Ramiro Quintanilla-Licea
Plants 2023, 12(11), 2203; https://doi.org/10.3390/plants12112203 - 2
Jun 2023
Cited by 2 | Viewed by 1807
Abstract Ruta chalepensis is an herb used to treat various ailments, and
its potential cytotoxic effects on different tumor cell lines have been
extensively studied. The present study aimed to evaluate the cytotoxic
activity of R. chalepensis methanol extract (RCME), sub-partitions
obtained from solvents [...] Read more.
(This article belongs to the Special Issue Bioactive Compounds in
Plants: Store House of Modern Drugs)
► Show Figures
18 pages, 12188 KiB
Open AccessArticle
Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis
through Suppression of Cancer Stemness Signaling and Induction of
Oxidative Stress-Associated Cell Death
by Ting-Yun Huang, Ching-Kuo Yang, Ming-Yao Chen, Vijesh Kumar Yadav,
Iat-Hang Fong, Chi-Tai Yeh and Yih-Giun Cherng
Nutrients 2023, 15(11), 2447; https://doi.org/10.3390/nu15112447 - 24
May 2023
Cited by 4 | Viewed by 1963
Abstract Background: Hepatocellular carcinoma (HCC) remains an
aggressive malignancy with a poor prognosis and a leading cause of
cancer-related mortality globally. Cumulative evidence suggests critical
roles for endoplasmic reticulum (ER) stress and unfolded protein
response (UPR) in chronic liver diseases. However, the role of [...]
Read more.
(This article belongs to the Special Issue The Role of Dietary Bioactive
Compounds on Liver Cancer and Non-alcoholic Fatty Liver Disease)
► Show Figures
21 pages, 2647 KiB
Open AccessArticle
Hogweed Seed Oil: Physico–Chemical Characterization, LC-MS Profile, and
Neuroprotective Activity of Heracleum dissectum Nanosuspension
by Daniil N. Olennikov and Nadezhda K. Chirikova
Life 2023, 13(5), 1112; https://doi.org/10.3390/life13051112 - 29 Apr
2023
Cited by 2 | Viewed by 1745
Abstract The seeds of dissected hogweed (Heracleum dissectum Ledeb.,
Apiaceae) are the source of hogweed oil (HSO), which is still
underexplored and requires careful chemical and biological studies. The
performed physico–chemical analysis of HSO elucidated basic physical
characteristics and revealed the presence of [...] Read more.
(This article belongs to the Special Issue Polyphenolic Compounds and
Their Nanoformulation: Metabolism and Impact on Human Health)
► Show Figures
18 pages, 1344 KiB
Open AccessArticle
Studies on the Accumulation of Secondary Metabolites and Evaluation of
Biological Activity of In Vitro Cultures of Ruta montana L. in Temporary
Immersion Bioreactors
by Agnieszka Szewczyk, Andreana Marino, Maria Fernanda Taviano, Lucia
Cambria, Federica Davì, Monika Trepa, Mariusz Grabowski and Natalizia
Miceli
Int. J. Mol. Sci. 2023, 24(8), 7045;
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