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From: Joe Gwinn <joegwinn@comcast.net>
Newsgroups: sci.electronics.design
Subject: Re: OT: Dynamic DNA structures and the formation of memory
Date: Mon, 13 May 2024 10:39:58 -0400
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On Mon, 13 May 2024 09:54:26 -0400, Joe Gwinn <joegwinn@comcast.net>
wrote:

>On Sun, 12 May 2024 18:30:32 -0700, John Larkin
><jjSNIPlarkin@highNONOlandtechnology.com> wrote:
>
>>On Sun, 12 May 2024 21:21:56 -0400, "Tom Del Rosso"
>><fizzbintuesday@that-google-mail-domain.com> wrote:
>>
>>>John Larkin wrote:
>>>> On Sun, 05 May 2024 05:36:06 GMT, Jan Panteltje
>>>> <pNaonStpealmtje@yahoo.com> wrote:
>>>>
>>>>> Dynamic DNA structures and the formation of memory
>>>>> https://www.sciencedaily.com/releases/2024/05/240501125755.htm
>>>>> Summary:
>>>>> An international collaborative research team has discovered that
>>>>> G-quadraplex DNA (G4-DNA) accumulates in neurons and dynamically
>>>>> controls the activation and repression of genes underlying long-term
>>>>> memory formation.
>>>>>
>>>>>
>>>>>
>>>>> I have always though that memory could be stored as DNA sequenxes...
>>>>
>>>> More likely RNA or some other protein.
>>>>
>>>> The oft-mocked Lamarckian concept, of genetic learning (not just
>>>> natural selection) is probably real, and some reverse transcription
>>>> does happen, namely that DNA is edited within the life of one
>>>> organism. But remembering where you left your glasses is probably
>>>> handled at a lower level than editing your chromosones.
>>>
>>>But how can it be passed down as Lamarck thought, if the eggs in the 
>>>ovaries are formed early? If genetic memory could be passed down it 
>>>would be only from the father because sperm are formed recently. But the 
>>>sperm spawn from local cells. If DNA is edited to store memory then 
>>>would these changes be duplicated in all cells in all tissues? How else 
>>>would the changes get into sperm cells? How could they get into eggs?
>>>
>>
>>If it is advantageous for a woman's life experiences to be passed onto
>>her children, nature will find a way.
>
>Yes, but that is not the issue.  Lamarck claimed that it could be done
>very quickly, in the lifetime of one woman, versus over generations
>(where DNA controls).  Actually, Lamarck was focused on Wheat,
>specifically can one train wheat to grow in Siberia; this was very
>attractive to Stalin.  Turns out you cannot.

In Stalin's day, it was Lysenko who sold Lamarckism to Stalin.  Pretty
well destroyed Russian Biology, which never really recovered.

..<https://en.wikipedia.org/wiki/Lysenkoism>

Joe Gwinn


>But there is a twist.  There was a study of the effect of mass
>starvation of the Swedish population which showed that one could
>detect the effect of starvation of grandfathers on their
>grandchildren.  It is thought that this is mediated by epigenetic
>information carried in methyl tags on the DNA, but I don't know if
>that was ever sorted out.  "Överkalix study":
>
>.<https://en.wikipedia.org/wiki/%C3%96verkalix_study>
>
>Joe Gwinn