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From: RonO <rokimoto557@gmail.com>
Newsgroups: talk.origins
Subject: Re: Guardian article on dairy influenza
Date: Tue, 25 Feb 2025 18:19:23 -0600
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On 2/24/2025 3:45 PM, RonO wrote:
> On 2/24/2025 3:21 PM, RonO wrote:
>> https://www.theguardian.com/us-news/2025/feb/22/bird-flu-virus-trump
>>
>> They note that the US does not have a handle on the spread of the 
>> dairy epidemic, and claim that the virus is now endemic to cattle, as 
>> it should have been concluded with the first dairy to dairy 
>> infections. Their little diagram about how the virus is spread is 
>> inaccurate because the cow to poultry spread is obviously mediated 
>> through human dairy workers that work on both poultry farms and 
>> dairies.  That has been known since the USDA released their June 2024 
>> report acknowledging that 2 dairy workers from infected dairies also 
>> worked at two poultry farms that got infected in Michigan.  They also 
>> note that the recent report (initiated in May 2024 and delayed for 
>> some reason until now) claimed evidence for human transmission of the 
>> dairy virus from dairy workers to their cats.
>>
>> The claim is that Trump's stupidity is just making the situation 
>> worse, but the USDA and CDC were already not doing much to contain the 
>> spread of the dairy virus before Trump started messing with the 
>> situation.  We have obviously known that there was human transmission 
>> of the virus since May and June of 2024, but nothing was done about 
>> it.  California confirmed by contact tracing that humans were 
>> spreading the virus in October 2024, and still they did nothing to 
>> restrict dairy worker movements between dairies and poultry farms and 
>> ended up with nearly all their dairies infected and 40% of their layer 
>> flocks lost.  The dairy worker testing that was supposed to have 
>> started in Nov. 2024 never happened, and the CDC is still claiming 
>> only around 700 total humans have been tested.  They have a pretty 
>> good idea that humans are spreading the D1.1 genotype in Nevada (all 
>> dairies have been infected with the same virus with the mutation to 
>> facilitate replication in mammals and one dairy worker has already 
>> been confirmed to be infected in early Feb yet they never started 
>> dairy worker testing in order to treat the infected dairy workers and 
>> stop the spread to other dairies.
>>
>> Ron Okimoto
>>
> 
> https://www.cidrap.umn.edu/avian-influenza-bird-flu/h5n1-strikes-more- 
> poultry-4-states-cdc-updates-details-recent-human-cases
> 
> Poultry flocks in 4 more states have gone down with avian influenza. The 
> CDC has confirmed that Wyoming and Ohio recent human cases both had 
> respiratory symptoms that required hospitalizations, but the CDC did not 
> release sequence informaion on the two infections, nor provide the 
> genotype of the virus infecting both cases.  Most likely this is the 
> D1.1 genotype that displayed critical respiratory symptoms in the 
> Canadian and Louisiana cases (the Louisiana patient died).  The Wyoming 
> patient is still in the hospital, but the Ohio patient is now recovering 
> at home.
> 
> Another Dairy herd in Nevada has been found to be infected (8 total) and 
> they still are not testing dairy workers nor restricting dairy worker 
> movements, and more dairies continue to be infected.  It seems to be 
> just nuts that no one wants to do what needs to be done in order to keep 
> more poultry flocks and dairy herds from being infected.  At this point 
> some of the dairy workers infected with the D1.1 genotype could be 
> leaving Nevada to other states.  7 dairies in Nevada are now infected 
> with the D1.1 genotype (1 dairy was found to be positive for the B3.13 
> virus several months ago).  Nothing is being down to stop that from 
> happening.
> 
> Ron Okimoto
> 
https://www.cidrap.umn.edu/avian-influenza-bird-flu/analysis-suggests-h5n1-d11-genotype-may-have-jumped-nevada-cows-weeks

https://virological.org/t/timing-and-molecular-characterisation-of-the-transmission-to-cattle-of-h5n1-influenza-a-virus-genotype-d1-1-clade-2-3-4-4b/991

The paper hasn't passed peer review at this time, and the USDA has not 
provided the source of the 4 cow samples, so they assume that the 
samples came from the same dairy because the sequences are so similar 
(one with several sequence variants and 3 nearly identical).  In the 
initial USDA annoucement the claim was that 4 dairies had been confirmed 
to be positive and that 4 milk samples had been sequenced and found to 
have the D1.1 genotype and that all 4 had the same PB2 mutation.  My 
take is that it is unlikely that the USDA would do a genome sequence on 
4 samples from one dairy when they had 4 positive dairies producing 
those samples.  The study may be wrong about how many farms are 
represented by the sequences.  It could be that 3 of the farms just 
shared the same vector of infection.  This would have been unlikely to 
have been a cow shared between 3 farms, and my guess is that it was an 
infected dairy worker.  They claim evidence that the infection entered 
the Nevada dairy herds a month before it was first detected in early 
January.

Ron Okimoto